Syphilis screening during Antenatal Care The syphilis bacterium can infect the baby of a woman during her pregnancy. All pregnant women should be tested for syphilis at booking. The syphilis screening test should be repeated during the third trimester (28 to 32 weeks gestation). Depending on how long a pregnant woman has been infected, she may have a high risk of having a stillbirth (a baby born dead) or of giving birth to a baby who dies shortly after birth; untreated syphilis in pregnant women
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