ASMR Cranial Nerve Exam
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ASMR Cranial Nerve Exam
ASMR Cranial Nerve Exam
173K viewsOct 28, 2022
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#Acetylserotonin O-methyltransferase Function
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Histamine symptoms flaring at the first time of strong emotion? COMT may be part of the picture. 😳 COMT (catechol-O-methyltransferase) is an enzyme that helps break down stress neurotransmitters like dopamine, norepinephrine, and epinephrine. It also relies heavily on methylation, which is the same biochemical process your body uses to clear histamine through the HNMT pathway. When COMT is slow, stress hormones linger longer. When stress hormones stay high, mast cells become more reactive. And
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Histamine symptoms flaring at the first time of strong emotion? COMT may be part of the picture. 😳 COMT (catechol-O-methyltransferase) is an enzyme that helps break down stress neurotransmitters like dopamine, norepinephrine, and epinephrine. It also relies heavily on methylation, which is the same biochemical process your body uses to clear histamine through the HNMT pathway. When COMT is slow, stress hormones linger longer. When stress hormones stay high, mast cells become more reactive. And
FacebookDr. Becky Campbell
604 views1 week ago
Histamine intolerance is not driven by histamine intake alone. It’s driven by impaired degradation. There are two primary histamine-clearing pathways: \t1.\tDAO (extracellular, gut-dependent) \t2.\tHNMT (intracellular, methylation-dependent) While DAO gets most of the attention, HNMT is responsible for clearing histamine inside tissues, including the brain, liver, and lungs. HNMT requires SAMe, which is generated through the one-carbon (methylation) cycle. This is where COMT (catechol-O-methyltr
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