HEREDITARY definition and meaning | Collins English Dictionary
HEREDITARY definition and meaning | Collins English Dictionary
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SMA is a hereditary condition, meaning it is passed down from parents to children. The most common form of SMA is caused by a defect in the SMN1 gene. This gene is responsible for producing the SMN protein, which is crucial for the survival of motor neurons. When the SMN1 gene is mutated, it can't produce enough SMN protein, leading to the degeneration and death of motor neurons. The loss of motor neurons in SMA causes progressive muscle weakness and atrophy. This can affect various muscles thro
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