@arcusmedicine on Instagram: "What is asterixis? Asterixis is a clinical sign seen on physical examination where the patient, when asked to extend their wrists and hold their arms out, shows a brief, involuntary lapse in muscle tone, causing a “flapping” motion of the hands. Where is it seen? It is a sign of metabolic encephalopathies, most commonly: • Hepatic encephalopathy • Uremia • CO₂ retention (respiratory failure) Mnemonic (optional): Asterixis = “A star (aster) is flapping its wings!”"