SOLVED: Calculate the hepatic clearance for drug with an intrinsic clearance of 12 Llmin normal adult patient whose hepatic blood flow is 1.5 Lmin: (b) If this same patient develops congestive heart failure that reduces his hepatic blood flow to Llmin but does not affect intrinsic clearance, what is the hepatic drug clearance this patient? (c) Calculate the extraction ratio for the liver in this patient before andafter congestive heart failure develops (d) From the above information, estimate th