Tight control of separase activity is essential for prolonged meiotic arrest of mammalian oocytes. Here, removal of securin and cyclin B1-Cdk1 dual inhibition of separase in mouse oocytes leads to ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...

The US administration has extended its line of attack on academia from US federal research to private universities. The abuse ...

Although student mobility is being restricted in a less dramatic fashion than currently in the USA, the impact on science ...

This study highlights novel genotype-driven metabolic adaptations in PM, laying the groundwork for targeted interventions ...

This study explores how mechanical signaling through membrane tension induces somal translocation during neuronal migration.

Stress granules are an integral part of the stress response that are formed from non-translating mRNAs aggregated with proteins. While much is known about stress granules, the factors that drive their ...

Uncapped free 20S proteasomes are abundant and active in cells, and yet their degraded intracellular protein substrates have remained underexplored. In their recent study, Sharon and colleagues ...

The migratory cardiac neural crest cells (CNCCs) contribute greatly to cardiovascular development. A thorough understanding of the cell lineages, developmental chronology, and transcriptomic states of ...

Two‐pore domain potassium (K2P) channels comprise a major and structurally distinct subset of the mammalian K + channel superfamily (Enyedi and Czirjak, 2010). The human genome contains 15 K2P channel ...

Policy‐makers have responded by calling for increased attention to be paid to the ethical, legal and social aspects of scientific research and technological developments. In particular, new and ...

Intracellular replication of the bacterial pathogen Salmonella enterica occurs in membrane‐bound compartments called Salmonella ‐containing vacuoles (SCVs). Maturation of the SCV has been shown to ...