Khamenei has condemned the attacks and promised to retaliate, saying Israel had "sealed for itself a bitter and painful destiny."

Israeli Prime Minister Benjamin Netanyahu spoke with ABC News' Jonathan Karl about Israel's attack on Iran's nuclear program and Iran's retaliation against his country.

Since Israel began its concerted attack on Iran on Friday, calls for regime change in Iran have grown louder – from hawks in the US Congress to Israeli officials and some Iranian activists abroad.

Lapid made a speech last month to Israel’s parliament, which is called the Knesset, that marked 600 days since the start of the war in Gaza. Lapid slammed Netanyahu for bringing a conflict upon Israel that didn’t exist during his own brief time in office.

Netanyahu reveals Iran attempted to assassinate both him and Trump, discusses Israel's strikes against Iran's nuclear program, and explains the "imminent threat."

The Kremlin responded Monday to remarks by Israeli Prime Minister Netanyahu on possible Iranian regime change, issuing a condemnation of the "actions" that have led to escalated tensions between the two Middle Eastern nations.

Netanyahu spoke after Trump earlier on Sunday called for a deal between the warring parties, saying “many calls and meetings” were now taking place that would lead to peace soon. “Iran and Israel should make a deal, and will make a deal,” he wrote on Truth Social.

Israeli Prime Minister Benjamin Netanyahu is on the mission of his lifetime. For years, the veteran leader has made the destruction of Iran’s nuclear program his top priority.

By Michael Martina and Katharine Jackson WASHINGTON (Reuters) -Regime change in Iran could be a result of Israel's military attacks on the country, Israeli Prime Minister Benjamin Netanyahu told Fox News on Sunday,

EXCLUSIVE: Israeli Prime Minister Benjamin Netanyahu doesn't rule out eliminating Iran's supreme leader in an ABC News interview.

During his second government, between 2009 and 2013, he tried at least twice to launch attacks against Iran’s nuclear programme but was stymied. He faced a series of obstacles. His generals and security chiefs opposed such a move.