Manitoba shatters grim record with sharp rise in newborns with syphilis

Manitoba is on track to have as many newborns infected with syphilis this year as the entire country did in 2019. The province had recorded 30 cases of congenital syphilis in babies as of Aug. 17, ...
eLife

Selective JAK Inhibition Reveals Paradoxical and Hierarchical Control of interferon-γ-driven Autoimmunity in AIRE Deficiency

These findings are important because they suggest that more selective JAK inhibition, particularly targeting JAK1 or JAK2, can effectively reduce organ pathology and pathogenic IFN-γ-producing immune ...