The Israel-Iran conflict has escalated into its fourth day with mounting casualties, widening attacks, and no sign of diplomatic resolution.

Iran is not winning this war, and they should talk, and they should talk immediately before it's too late,' Trump said at the G7 Summit in Canada.

TEL AVIV, Israel (AP) — Iran fired a new wave of missile attacks on Israel early Monday, killing at least five people, while Israel claimed in the fourth day of the conflict that it had now achieved “aerial superiority” over Tehran and could fly over the Iranian capital without facing major threats.

Israel's conflict with Iran represents far more than another Middle Eastern crisis—it marks the emergence of a dangerous new chapter in nuclear rivalries that has the potential to reshape global proliferation risks for decades to come.

Since Israel began its concerted attack on Iran on Friday, calls for regime change in Iran have grown louder – from hawks in the US Congress to Israeli officials and some Iranian activists abroad.

The war between Israel and Iran is in its fourth day, with Israel striking at military sites and Iran's nuclear program and Iran firing missiles in retaliation

US President Donald Trump expressed hope that Israel and Iran could reach a ceasefire amid ongoing hostilities but acknowledged that “sometimes they have to fight it out.” Trump said he believes there’s “a good chance” of a deal eventually being reached.

The conflict between Israel and Iran is heating up as damaging missile strikes continue on both sides. CBS News' Courtney Kealy has the latest updates.