The 109th running of the Indianapolis 500 is this Sunday at Indianapolis Motor Speedway. See who the experts and oddsmakers predict to win.

As of race day on Sunday morning, O'Ward (+475) and Palou (+475) are still favored to win, per BetMGM. But two-time defending Indy 500 champ Josef Newgarden jumped ahead of McLaughlin and Dixon and now has the third-best odds to win his third straight Indy 500 at +700 — despite being part of the Team Penske controversy this week.

Indianapolis 500 will take place on Sunday at Indianapolis Motor Speedway, as The Great American Race celebrates its 109th running.

The Indy 500 will take place this Sunday on FOX. Check out these fun ways that you can wager on the upcoming action.

Despite starting the Indy 500 on the pole, rookie Robert Shwartzman is hardly the favorite to win Sunday's race.

Palou started the year off in dominant fashion, winning four of the first five races of the 2025 season. The reigning Indy 500 champion is Josef Newgarden ... Check out the latest odds for "The Greatest Spectacle in Racing" at DraftKings Sportsbook ...

Patrick Everson breaks down the betting action for the "Greatest Spectacle in Racing," including a rookie in the driver's seat and a two-time champ looking for a three-peat.

Pole sitter Robert Shwartzman isn't getting much love from the sports books but we've got you covered with a longshot pick