Some foreign pharmaceutical plants that export generic drugs to the United States have glaring quality problems that can lead to drug shortages. There is a better way to assure the safety of ...

Untreated atrial fibrillation carries an approximately 3 to 5% annual risk of ischemic stroke. Long-term oral anticoagulation therapy decreases this risk to 1.7% with warfarin and to 1.5% with ...

Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. We ...

Data are needed on the effect of oxygen delivered through a high-flow nasal cannula, as compared with standard oxygen therapy, on intubation and mortality in patients with acute hypoxemic ...

Patients with atrial fibrillation and a moderate-to-high risk of stroke were randomly assigned, in a 1:1:1 ratio, to receive subcutaneous injection of abelacimab (150 mg or 90 mg once monthly) ...

In patients with refractory systemic lupus erythematosus, in vivo generation of CD19 CAR T cells by means of lipid nanoparticles led to B-cell depletion, reduced disease activity, and no major toxi ...

Explore this issue of The New England Journal of Medicine (Vol. 390 No. 3).

Supported by grants from the Deutsche Forschungsgemeinschaft, a grant (80735240) from the Deutsche Krebshilfe, the Else Kröner Fresenius Stiftung, the Else Kröner Clinician Scientist Program Munich: ...

A 54-year-old woman with metastatic breast cancer who was receiving denosumab therapy presented with right jaw pain. An area of exposed, necrotic bone was visualized in the right mandible.

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 23).

Sotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated KRAS G12C (N Engl J Med 2023;389:2125-2139). As a result of late data entry, a reanalysis using a later data snapshot (March ...

To the Editor: Morin and Buysse (July 18 issue) 1 provide a comprehensive overview of current assessments and treatments for insomnia. Their emphasis on cognitive behavioral therapy for insomnia as a ...