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The Rams and Panthers last met in Week 6 of the 2022 season, a 24-10 Rams victory. Quarterback Matthew Stafford threw for 253 yards and one touchdown against one interception, and wide receiver Cooper Kupp caught seven passes for 80 yards. The Rams held Carolina to 110 net passing yards and its lone score came on defense.

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At 6-5 with a playoff berth within reach, the Carolina Panthers roll into primetime carrying equal parts urgency and belief. Across the field, the 7-4 San Francisco 49ers enter Monday night trying to steady themselves after an uneven stretch,

The Los Angeles Rams, led by quarterback Matthew Stafford, face the Carolina Panthers, led by quarterback Bryce Young, on Sunday, Nov. 30, 2025 at Bank of America Stadium in Charlotte, N.C.

Both teams are fighting for playoff positioning as they meet by the Bay on Monday night. On Monday, Nov. 24, Week 12 of the NFL season will wrap up at Levi’s Stadium as the San Francisco 49ers (7-4) face the Carolina Panthers (6-5).

The Rams are an 8-point favorite over the Cardinals in NFL Week 14 odds for the game, courtesy of BetMGM Sportsbook. Los Angeles is -425 on the moneyline, while Arizona is +325. The over/under (point total) is set at 48.