DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...

Tracking the genetic diversity of SARS-CoV-2 in wastewater, rather than just viral abundance, dramatically improves the ...

Researchers have developed a comprehensive atlas that maps DNA methylation—a critical chemical modification governing gene activity—across 39 human cell types, revealing a complex landscape of ...

DNA methylation is an epigenetic modification crucial to normal development, with its dysregulation leading to various diseases including cancer. As interest in epigenomics grows, an innovative ...

An illustration of multicolored tangle of threads within a small black sphere. A 3D illustration shows DNA packaged into the nucleus, scientists with the 4D Nucleome project are now building accurate ...

Scientists have identified 345 genes tied to six major neuropsychiatric disorders by mapping their activity in specific brain and immune cell types. The work, integrating single-cell genetic data with ...

Bionano Genomics and Greenwood Genetic Center have announced a study published in Genome Research, marking the first use of optical genome mapping (OGM) to explore the genetic factors behind neural ...

Biological processes associated with genes linked to promoter–enhancer pairs in normal and cancerous tissues: brain (D), breast (E), and pancreas (F). Each row represents a group of genes sharing a ...

Researchers at Lund University have produced the most detailed map yet of the epigenome in pancreatic cells that regulate blood sugar, revealing DNA methylation changes linked to type 2 diabetes. The ...