Medically reviewed by Jeffrey S. Lander, MD Key Takeaways Combining blood pressure medications, such as a long-acting calcium channel blocker with an ACE inhibitor or ARB, is often more effective than ...

Please provide your email address to receive an email when new articles are posted on . Drug classes used as monotherapy for hypertension were shown to be comparable, although thiazide or ...

An angiotensin-converting-enzyme (ACE) inhibitor, the most common first-line approach for newly diagnosed hypertension, is not as effective and causes more adverse effects than a thiazide diuretic, a ...

Kidney stones affect nearly 10% of the global population. For more than three decades, thiazide diuretics, a common medication used for high blood pressure, have been the standard of care for kidney ...

Nephrolithiasis can persist after treatment with extracorporeal shock-wave lithotripsy (ESWL). Thiazide diuretics reduce the renal excretion of calcium and have been used to treat calcium ...

The sodium–chloride cotransporter (NCC) is a protein dimer central to sodium handling by the kidney and is the target of an important class of drug for high blood pressure called thiazide diuretics.

THE usefulness of thiazide diuretics in clinical practice has been established. Particular interest in these compounds stems from several reports concerning their effect on carbohydrate metabolism.

Please provide your email address to receive an email when new articles are posted on . The cumulative incidence of hyponatremia was about 1.4 percentage points higher for thiazide diuretics than ...

In rural regions of Africa, high blood pressure often goes untreated because health centers are far away and there is a shortage of health professionals. A study in Lesotho shows that, with the help ...