Cytotoxic T lymphocytes are the body's specialized "killers", precisely eliminating infected or cancerous cells. Their action relies on a specialized exchange zone called the "immune synapse", ...

Researchers found that lowering MHC I can expose cancerous or foreign cells to CD4+ T cell attack, reshaping assumptions ...

Chimeric antigen receptor T-cell therapy—CAR T for short—has been a major advance in treating blood cancers like leukemia and lymphoma. But the immunotherapy has struggled against solid tumors for two ...

Cytotoxic T lymphocytes are the body's specialized "killer" cells, precisely eliminating infected or cancerous cells. Their action relies on a specialized exchange zone called the "immune synapse," ...

Balancing the immune system is a delicate act. If it’s too weak, infections and cancer can take hold; if it’s too strong, autoimmune diseases or transplant rejection can occur. Researchers have ...

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers report. The aptamers -- short ...

The body’s “killer” T cells don’t just attack—they strike with astonishing precision, forming a tiny, highly organized contact zone that lets them destroy dangerous cells without harming their ...

Drug-delivering aptamers that can precisely target leukemia stem cells with enhanced potency have been developed. Delivering anticancer drugs with specificity and potency to cancer stem cells is an ...

Though CAR T cells have been effective against certain blood cancers, they have not been for solid tumors. Now, a new form of highly sensitive CAR T cells aims to overcome one of the biggest barriers ...