Saved from precursor B-cell acute lymphoblastic leukemia, the Nobel Prize winning CAR T-cell therapy gave Bryn Ailinger a very merry Christmas ...

Researchers at the Johns Hopkins Kimmel Cancer Center’s Ludwig Center developed a new treatment that selectively targets ...

Researchers released a consensus statement with recommendations to update T cell nomenclature and improve communication ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before. This breakthrough may help explain why immunotherapy works for some ...

In a person living with HIV, proviruses—strands of HIV DNA—are typically integrated into the T cell genome and become a permanent part of the cell's genetic makeup. This integration enables the ...

It develops from the abnormal multiplication of T cells, or T-lymphocytes, a type of white blood cell essential for immune system function. The specific treatment course and prognosis for T-cell ...

When killer T cells of our immune system divide, they normally undergo asymmetric cell division (ACD): Each daughter cell ...

On February 13, Allogene Therapeutics published new long-term follow-up data on cemacabtagene ansegedleucel, showing the investigative allogeneic chimeric antigen receptor (CAR) T-cell therapy ...

An expert discusses IL-18-armored CAR T cells for adults with relapsed B-cell leukemia, showing complete remissions with ...

Engineered cell products such as CAR T cells have demonstrated considerable therapeutic potential. Two studies in Science report new avenues to expand the applications of synthetic cell therapies – ...

Researchers at the Johns Hopkins Kimmel Cancer Center's Ludwig Center developed a new treatment that selectively targets ...