Sequence analysis encompasses the computational examination of biological polymers—DNA, RNA and proteins—to elucidate their structure, function and evolutionary relationships. At its core lies the ...

Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

Historical introduction and overview -- Collecting and storing sequences in the laboratory -- Alignment of pairs of sequences -- Introduction to probability and statistical analysis of sequence ...

The Advances in Genome Biology and Technology (AGBT) meeting celebrated its 25 th anniversary in sunny Marco Island, Florida, with the customary mix of big name speakers addressing researchers and ...