RNA and DNA are chemical cousins. But one tiny difference between them (an extra oxygen atom repeated along RNA’s backbone) ...

In most modern cells, DNA stores the genetic blueprint, and relies on proteins to replicate, repair and build from those blueprints. At the same time, proteins require instructions from DNA to be made ...

Researchers from Children's Hospital of Philadelphia (CHOP) developed a new RNA sequencing strategy that can reveal how genetic variants disrupt gene function and improve the diagnosis of rare ...

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

Although there are striking differences between the cells that make up your eyes, kidneys, brain and toes, the DNA blueprint for these cells is essentially the same. Where do those differences come ...

A newly revealed “aging cliff” in sperm RNA marks a conserved molecular transition from youth to later life, offering fresh insight into how a father’s age may influence the earliest stages of ...

One of the greatest mysteries of our planet is how a soup of lifeless chemicals transformed into the first living cell. There are several competing theories about where this happened, from frozen ...

Different types of cancer have unique molecular "fingerprints" which are detectable in early stages of the disease and can be picked up with near-perfect accuracy by small, portable scanners in just a ...