How do related proteins develop different functions? This is the question investigated by a research team involving Kiel ...

Cell surface protein labeling supports precise characterization of immune checkpoints, receptors, and other therapeutic ...

Hypertrophic cardiomyopathy (HCM) is a genetic disease associated with sudden cardiac death. Variants in alpha-actinin-2 (ACTN2), a Z-disc protein that anchors actin thin filaments have been ...

Removing a single amino acid can determine whether new proteins assemble into stable complexes within mitochondria. An enzyme ...

A previously unknown protein, hidden in RNA thought not to encode proteins, helps cells divide correctly. The RNA molecule ...

Some proteins in human cells that are implicated in cancer also have causal roles in neurodevelopmental disorders, raising the possibility of repurposing targeted cancer therapies to help address ...

Scientists have often thought of cells as small, bustling cities with parts that resemble factories, power grids and shipping ...

Proteomics is the large-scale study of proteins, particularly their structures and functions. It involves the systematic identification, quantification, and analysis of the entire protein complement ...

Proteins, the pillars of cellular function, often assemble into 'complexes' to fulfill their functions. A study reveals why this assembly often begins during the very process of protein synthesis or ...

Researchers at Yale School of Medicine have conducted the first comprehensive structural analyses of a class of proteins whose dysfunction is associated with neurodegenerative diseases. In two new ...

Researchers have discovered a previously unknown cell-protecting function of a protein, which could open new avenues for treating age-related diseases and lead to healthier aging overall. McMaster ...