Polygenic scores (PGSs) have transformed human genetic research and have numerous potential clinical applications. Here we present a series of recent enhancements to the PGS Catalog and highlight the ...

Important new updates to the largest open database for polygenic scores, the Polygenic Score (PGS) Catalog, could help to generate more equitable disease risk predictions for a diverse range of ethnic ...

Polygenic scores (PRSs) are derived by summing genome-wide genetic variants associated with a given trait or disease. As aggregates of genetic variants’ effects, they are used to predict disease risk.

Not all cancers are alike, especially when it comes to prostate cancer. “The guidelines recommend they go on active surveillance rather than getting treated. For many of them, it’s really unlikely ...

Polygenic scores are a source of considerable debate in the biomedical and healthcare communities. Can they or can they not provide information that can be used in the prevention of common complex ...

“What makes the score so powerful is its ability to predict, before the age of five, whether a child is likely to develop obesity in adulthood, well before other risk factors start to shape their ...

Polygenic risk scores (PRS) combined with clinical factors improve POAG risk prediction, aiding in identifying high-risk patients. The study used OHTS data, showing low polygenic risk correlates with ...

A risk score incorporating genetic variants for open-angle glaucoma is accurate enough to help with diagnosis of the condition, an interim study reveals. Although hundreds of genetic changes are ...

A new analysis explores the genetic liability of psychiatric disorders using polygenic scores and recurrent copy number variants.

Share on Pinterest A new genetic tool could help identify those at higher risk for 8 heart-related conditions. Image credit: weerapatkiatdumrong/Getty Images Research suggests a new polygenic risk ...

Please provide your email address to receive an email when new articles are posted on . Researchers developed a multi-ancestry polygenic score using data from two genome-wide association studies.

Data from a large prospective cohort study reveal that a polygenic risk score has the potential to predict survival outcomes in patients with breast cancer. Arya Mariam Roy, MBBS, Hematology/Oncology ...