In most eukaryotes, the inheritance of mitochondrion and its DNA (mtDNA) is strictly maternal, despite the fact that a spermatozoon can inject up to 100 functional mitochondria into the oocyte during ...

The 100 or so organelles in sperm are swamped by hundreds of thousands of mitochondria embedded in each egg cell — each carrying the 37 genes in mitochondrial DNA. The contribution of only maternal ...

A new study from deCODE genetics uses pedigrees and sequence data from 64,806 Icelanders to shed light on the rate and nature of mutations in mitochondrial DNA (mtDNA) and the peculiar dynamics of its ...

Doubly uniparental inheritance (DUI) of mitochondrial DNA (mtDNA) represents a rare and intriguing deviation from the standard model of strictly maternal inheritance. In bivalves, DUI manifests as the ...

The human genome is contained in the nucleus of almost every cell in the body. But those cells also contain multitudes of mitochondria, and these incredible little power-generating organelles carry ...

The tiny little powerhouses of our cells, the mitochondria, are unique among organelles because they carry their own tiny little genomes... | Genetics And Genomics ...

Recombination occurs in human mitochondrial DNA, says a team from the Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, in a “proof of concept” paper in Science this week that ...

Management of mitochondrial-related heart disease relies on multidisciplinary care and symptom control, as targeted gene-editing therapies are limited.

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...