Study reveals a specific genetic mismatch linked to life-threatening transplant complications

Umbilical cord blood transplantation has transformed the treatment options for patients with blood cancers and other ...
Heart

Prosthetic annulus size mismatch and recurrent mitral regurgitation after repair in advanced degenerative disease

Background Recurrent mitral regurgitation (MR) remains a major limitation of mitral valve (MV) repair in patients with ...
Nature

Mismatch repair status may predict response to adjuvant chemotherapy in resectable pancreatic ductal adenocarcinoma

Deficiencies in DNA mismatch repair have been associated with inferior response to 5-FU in colorectal cancer. Pancreatic ductal adenocarcinoma is similarly treated with pyrimidine analogs, yet the ...
ascopubs.org

Genomic Microsatellite Signatures Identify Germline Mismatch Repair Deficiency and Risk of Cancer Onset

Outcomes for Children With Type II and Type III Pleuropulmonary Blastoma Following Chemotherapy: A Report From the International PPB/DICER1 Registry We developed and analyzed a functional Low-pass ...