IN the skin of mice painted with chemical carcinogens a remarkable accumulation of mast cells is usually observed in the altered dermis. Cramer and Simpson 1 first observed that the accumulating mast ...

Immune cell trapping during allergic responses Mast cells, residing in tissues and critical for initiating inflammation, are filled with granules containing pro-inflammatory substances. These granules ...

Mast cell precursor cells do not just cause an increase in mature mast cells during inflammation, they also play an active role in diseases like asthma, according to a new study. Mast cell precursor ...

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy ...

Scientists at Zhejiang University have found a way to turn allergy-causing cells in the body into cancer-fighting agents, offering a new targeted approach that combines immune system activation with ...

One viewer is asking what mast cell activation syndrome (MCAS) is and what symptoms come along with it. Dr. Lacy Anderson responds. Mast cell activation syndrome is a condition where people have ...

For many patients with diverse and seemingly unrelated symptoms, obtaining an accurate diagnosis can take years of specialist visits and inconclusive tests. Mast cell activation syndrome, a disorder ...

In early 2020, Wynde Dyer walked into the house that would transform her life. The Central California ranch sat on a cul-de-sac of gated homes and glittering aquamarine pools. It boasted private ...

This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...