Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...
Scientists have uncovered a surprising twist in how cells behave when division goes wrong. Sometimes a cell successfully copies its DNA but fails to split into two, leaving it with double the genetic ...
Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic tangles overwhelm normal repair pathways, cells flip on a fast but error-prone ...
Damaged DNA can escape from one human cell and infiltrate another. Like prisoners tunneling out of jail, this DNA travels via tubelike structures between neighboring cells, scientists report May 19 in ...
A new technology allows scientists to map, in single cells, the DNA binding sites of transcription factors and other ...
Morning Overview on MSN
The DNA from a single human cell would stretch about two meters if pulled into a line
Stretched into a single line, the DNA packed inside one human cell would reach roughly two meters, yet it folds into a ...
Morning Overview on MSN
Cells that double their DNA through failed division survive far better than those from botched chromosome splits, a clue to how some cancers take hold
Cells that acquire a doubled genome after a failed division step survive and proliferate far more effectively than cells left ...
Researchers at Genentech Inc. and UC Davis have worked out the structure of the RAD51 complex, which repairs breaks in DNA. When DNA experiences a double-strand break, enzymes trim back one of the two ...
While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...
The left-handed spiral of each Z-DNA strand is highlighted on the left. Binding and bonding of the two zinc finger domains (shown in red) from the CTCF protein to Z-DNA (shown in blue). This protein ...
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