Long before a liver tumor appears, a high-fat diet can push liver cells into a risky survival mode. That is the central ...

Understanding how these functions impact a given compound is essential for effective preclinical drug development. Hepatocytes comprise approximately 80 % of the liver’s volume but only represent ...

One of the biggest risk factors for developing liver cancer is a high-fat diet. A new study from MIT reveals how a fatty diet ...

Liver cells exposed to a high fat diet revert to an immature state that is more susceptible to cancer-causing mutations.

Bone marrow contains stem cells with the potential to differentiate into mature cells of various organs. We determined whether circulating stem cells have a similar potential. Biopsy specimens from ...

Donor organ shortage is still the major obstacle for the clinical application of hepatocyte transplantation in the treatment of liver diseases. However, generation of hepatocyte-like cells from ...

Researchers at the Kanazawa University Graduate School of Medical Sciences report in PLOS Pathogens a novel role for the ...

What am I looking at? This is a single human hepatocyte. Its two nuclei are in blue (1). The other colors in this image are stains of the actin protein and are depth-coded, with red being the closest ...