Despite improved diagnosis and treatment options, coronary artery disease (CAD) is still the leading cause of mortality and morbidity worldwide. Established risk factors such as smoking, ...

The top panel, designed with BioRender.com, illustrates the process of clot formation and lysis, beginning with platelet aggregation and activation of the coagulation cascade, followed by the ...

A group of researchers from the United States discovered that the spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can induce the formation of highly inflammatory ...

Fibrin plays a major role in stopping bleeding and healing wounds. However, if fibrin is formed in excess, e.g., in chronic wounds, thrombosis and subsequent vascular occlusions can occur. Therefore, ...

However, additional thrombin generation and fibrin formation, maturation of the fibrin network, and generation of antifibrinolytic mechanisms that protect the clot from premature degradation occur ...

The glycoprotein V of the blood platelets is an important switch point for haemostasis and thrombus formation. This new finding could have great clinical potential. When our blood vessels are injured ...

Pulmonary embolism is a condition caused by a blood clot in the lungs that cuts blood flow to major blood vessels. The primary function of blood clots is to stem blood loss from ruptured blood vessels ...

The developing thrombus in a living mouse after vessel-wall injury (Panel A) is characterized by the deposition of platelets (red), tissue factor (green), and fibrin (blue). Platelet thrombus ...