Embryo development in livestock underpins global food security and genetic improvement programmes. From the first mitotic divisions in the zygote to the formation of the blastocyst, the timing, ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...

The Plachta lab has pioneered the use of live-imaging approaches to discover how the preimplantation embryo forms in real ...

A small tissue fold in fly embryos, once thought purposeless, plays a vital role in stabilizing tissues. Researchers show that it absorbs stress during early development, and its position and timing ...

New research sheds light on embryonic mitosis, thanks to a combination of novel imaging techniques, CRISPR/Cas9 genome editing technology, a modern protein-knockdown system, and medaka, or Japanese ...

A new study shows that the embryo and the uterine lining conduct an active "conversation" from the very earliest stages of implantation. They engage in a back and forth of tiny packages called ...

Obstetricians and gynecologists at Toho University, Japan examined 1,331 cases of frozen-thawed embryo transfer cycles and found that blastocysts showing shrinkage at the time of transfer had a low ...

Scientists are exploring ways to mimic the origins of human life without two fundamental components: sperm and egg. They are coaxing clusters of stem cells – programmable cells that can transform into ...

Only about one out of three conceptions leads to birth. 1 Approximately a third of embryos fail to attach to the uterus, while another third is lost after the embryo implants. “Human reproduction is ...

Scientists have evaluated the adverse effects of blastocyst shrinkage on the reproductive outcomes of frozen-thawed embryo transfer. The effect was evident in embryos with morphologically ...