How does DNA recombination work? It occurs frequently in many different cell types, and it has important implications for genomic integrity, evolution, and human disease. In the alternate pathway ...
The active uptake of extracellular DNA and its genomic integration is termed natural transformation and constitutes a major horizontal gene-transfer mechanism in prokaryotes. Chromosomal DNA ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 4 (Feb. 19, 2002), pp. 2100-2105 (6 pages) Integration of foreign DNA was observed in the Gram-positive ...
In examples 1 and 4 of Figure 1, we examined the target region in the parent molecule after ET recombination to determine whether it had been copied into the subclone, or excised from the parent. In ...
“TAR cloning is used to genetically engineer synthetic viruses with novel properties that may be used for the development of new vaccines.” Transformation-associated recombination (TAR) cloning ...
November 4, 2010 – The autoimmune disease type 1 diabetes (T1D), also known as juvenile diabetes, is diagnosed in approximately 70,000 children worldwide per year. Genetics is increasingly being ...
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Boosting precision gene editing: Autophagy shifts DNA repair toward homologous recombination
Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A Korean research team has become the first in the world to significantly ...
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