A gene-editing tool that can turn genes on and off like a light switch has been developed. Turning a gene on means activating ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

New research suggests that alternative splicing may have an even greater influence on biology than just by creating new protein isoforms. The study shows that the biggest impact of alternative ...

In a recent study published in the journal Nature Biotechnology, researchers describe the pA regulator system based on a ribonucleic acid (RNA)-based switch to regulate mammalian gene expression by ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

The processes that keep a cell alive are constantly challenged by unpredictable changes in its environment. Cells manage to counteract these changes by employing sophisticated regulatory strategies ...

Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, intriguingly, many of the most important proteins involved in gene ...

4 edition of Cell by MIT researchers shows the importance of understanding the disease as a battle over how well brain cells control the expression of ... Another example is the fate of neurons ...

Most people recognize Alzheimer's from its devastating symptoms such as memory loss, while new drugs target pathological aspects of disease manifestations, such as plaques of amyloid proteins. Now a ...