DNA replication stress is incurred by endogenous or environmental challenges to replication fork progression that impede faithful genome duplication. Genomic G-quadruplexes (G4s) are DNA secondary ...
DNA replication is the process by which a cell makes an identical copy of its DNA. This process is performed at the beginning of every cell division so that when the cell divides, each daughter cell ...
Oncogene activation causes replication stress, which is thought to drive genome instability and tumorigenesis 1. Certain regions of the genome, called common fragile sites (CFSs), are particularly ...
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