A Jacobs School researcher is focused on learning more about how tight junctions form naturally — and how their breakdown can lead to disease.

They showed that basal spot junctions not only helped cells adhere to one another but were important for regulating Hippo signalling. "Our discovery of basal spot junctions in epithelial tissues has ...

Epithelial tissues are in constant interaction with their environment. Maintaining their functionality requires dynamic balance (homeostasis) and that their cell numbers are tightly regulated. This is ...

Australian researchers have discovered a new way that epithelial cells, which form layers in organs like the skin and stomach, attach to one another, and how they perceive growth signals at these ...

Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first ...

Our bodies and organs are shielded from the external environment by tissue barriers like the skin. These barriers must be tightly sealed to prevent unwanted substances from entering. This sealing is ...

Intercellular forces generate distinct patterns of extrusion: high compressive forces (top panel) drive apoptotic cell extrusion toward the upper side, while lower compressive forces (bottom panel) ...