The DNA in our cells is constantly damaged, with the most severe being the simultaneous breakage of both strands that compose it. In a study published in Nature Communications, scientists reveal in ...

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. This discovery ...

Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...

Researchers have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. Researchers from the University of Birmingham have uncovered ...

A powerful new discovery reveals that Nup98 a protein once thought to only ferry molecules through the nucleus plays a vital role in safeguarding the most vulnerable areas of DNA. By forming ...

Using comparative molecular biology with human cGAS – which actually inhibits DNA repair – the scientists found that the naked mole-rat's enzyme has four key changes that facilitate the important work ...

Cars patched up after a wreck may look fixed—but never run quite as before. The same may hold true for chromatin, according to a study published in Science on November 6. In response to double-strand ...