Autoimmune polyendocrine syndrome type 1 (APS-1) responded to ruxolitinib (Jakafi) in a small study, researchers said, offering hope that one drug can relieve most of the symptoms of this rare but ...

Autoimmune polyendocrine syndrome Type 2 (APS-2) is a rare disorder characterised by progressive multi-glandular dysfunction, ...

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1). Researchers ...

Autoimmune Addison's disease (AAD) results from the immune-mediated destruction of adrenocortical cells. AAD is a major component of the autoimmune polyendocrine syndromes type 1 (APS 1) and type 2.

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1). Researchers ...

Investigators have found that the absence of autoimmune regulator (Aire) in mice results in fertility problems similar to those affecting men with autoimmune polyendocrine syndrome type I (APS-1).

A new study led by researchers at the National Institutes of Health’s (NIH) National Institute of Allergy and Infectious Diseases (NIAID) demonstrates a drug approved to treat certain autoimmune ...

Investigators have found that the absence of autoimmune regulator (Aire) in mice results in fertility problems similar to those affecting men with autoimmune polyendocrine syndrome type I (APS-1).

Cross-sections of lungs from mice with the gene deficiency that causes APS-1, showing damaged tissue in mice not administered ruxolitinib (left) and healthy tissue in mice administered ruxolitinib ...