The San Francisco 49ers released their latest injury updates headed into the Week 8 contest versus the Houston Texans.

This article was originally published on www.si.com/nfl/49ers as Multiple 49ers Pop Up on First Injury Report of Week 8. As usual, the San Francisco 49ers have a lengthy injury report to begin their practice week.

The 49ers are dealing with numerous injuries heading into their Week 5 "Thursday Night Football" matchup with the Rams. Here's a look at all of them.

The San Francisco 49ers were hoping their rookies would be ready to pick up the slack after injuries to so many veteran players. Those hopes were dashed in Houston.

As expected, the San Francisco 49ers officially ruled Brock Purdy and Ricky Pearsall out. Here is the list of players who won’t suit up against the Houston Texans in Week 8: QB Brock Purdy (toe) WR Ricky Pearsall (knee) C Jake Brendel (hamstring) DE Yetur Gross-Matos (knee, hamstring) DE Bryce Huff (hamstring)

The 49ers' are dealing with more injuries ahead of their Week 8 matchup versus the Texans. This features Brock Purdy and Ricky Pearsall.

Kyle Juszczyk explained why he believes San Francisco maintains its winning ways with backups stepping up amid injuries.

The long string of injuries that have haunted the San Francisco 49ers all season finally became too much to overcome for at least one week. The defense missing its top two players couldn't get off the field,