Houston-based Axiom Space launched its fourth crewed mission to the International Space Station (ISS) overnight, lifting off on a SpaceX Falcon 9 rocket from NASA's Kennedy Space Center (KCS), in Florida. The mission got underway early Wednesday, lifting off from KSC's Launch Complex-39A at 2:31 a.m. EDT (0631 GMT).

After a series of delays from weather to rocket engines to a leak on the International Space Station, NASA has cleared the way for SpaceX to launch the Axiom Space Ax-4 crew on the Space Coast.

It's the fourth mission to the International Space Station for Axiom Space. The Houston company works with SpaceX for rides to the station and coordinates with NASA to use the ISS for its astronauts.